B-hIGF2R mice
| Strain Name | C57BL/6-Igf2rtm1(IGF2R)Bcgen/Bcgen | Common Name | B-hIGF2R mice |
| Background | C57BL/6 | Catalog number |
110986 |
| Aliases | IGF2R(CD222, CI-M6PR, CIMPR, M6P-R, M6P/IGF2R, MPR 300, MPR1, MPR300, MPRI) | ||
Strain specific analysis of IGF2R gene expression in wild-type mice and B-hIGF2R mice by RT-PCR. Mouse Igf2r mRNA was detectable in splenocytes of wild-type mice (+/+). Human IGF2R mRNA was detectable only in homozygous B-hIGF2R mice(H/H) but not in wild-type mice.
Strain specific IGF2R expression analysis in homozygous B-hIGF2R mice by western blot. Heart tissue, kidney tissue and spleen tissue were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hIGF2R mice (H/H), and analyzed by western blot with anti-hIGF2R antibody. Human IGF2R was detectable in wild-type mice and homozygous B-hIGF2R mice, as the antibody is crossly reactive with IGF2R in human and mice.
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