Strain Name
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C57BL/6-Il17rbtm1(IL17RB)/Bcgen
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Common Name
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B-hIL17RB mice
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Background
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C57BL/6
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Catalog number
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110090
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Related Genes
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IL17RB, interleukin 17 receptor B, CRL4, EVI27, IL17BR, IL17RH1
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NCBI Gene ID
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50905
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mRNA expression analysis
Strain specific analysis of IL17RB gene expression in wild type (WT) mice and B-hIL17RB mice by RT-PCR.
Mouse Il17rb mRNA was detectable only in thymus of WT mice (+/+). Human IL17RB mRNA was detectable only in homozygous B-hIL17RB mice (H/H) but not in WT mice (+/+).
Protein expression analysis-Macrophages
Strain specific IL17RB expression analysis in homozygous B-hIL17RB mice by flow cytometry.
Splenocytes were collected from wild type (WT) mice (+/+) and homozygous B-hIL17RB mice (H/H), and analyzed by flow cytometry with species-specific anti-IL17RB antibody. Mouse IL17RB was detectable in WT mice (+/+) mice due to the cross-reactivity of antibodies. Human IL17RB was detectable in homozygous B-hIL17RB mice (H/H).
Protein expression analysis-CD45+ cells
Strain specific IL17RB expression analysis in homozygous B-hIL17RB mice by flow cytometry.
Hepatocytes were collected from wild type (WT) mice (+/+) and homozygous B-hIL17RB mice (H/H), and analyzed by flow cytometry with species-specific anti-IL17RB antibody. Mouse IL17RB was detectable in WT mice (+/+) mice due to the cross-reactivity of antibodies. Human IL17RB was detectable in homozygous B-hIL17RB mice (H/H).