B-hIL19 mice
| Strain Name |
C57BL/6N-Il19tm1(IL19)Bcgen/Bcgen |
Common Name | B-hIL19 mice |
| Background | C57BL/6N | Catalog number |
111597 |
|
Related Genes |
IL-10C, MDA1, NG.1, ZMDA1 | ||
Strain specific analysis of IL19 gene expression in wild-type C57BL/6 mice and B-hIL19 mice by RT-PCR. Mouse Il19 mRNA was detectable in spleen of wild-type C57BL/6 mice (+/+) but not in homozygous B-hIL19 mice (H/H). Human IL19 mRNA was detectable only in homozygous B-hIL19 mice but not in wild-type mice.
Strain specific IL19 expression analysis in homozygous B-hIL19 mice by ELISA. Plasma was collected from wild-type C57BL/6 mice (+/+) and homozygous B-hIL19 mice (H/H) stimulated with or without LPS in vivo and analyzed by ELISA with strain specific anti-IL19 antibodies. Mouse IL19 was only detectable in wild-type mice. Human IL19 was only detectable in homozygous B-hIL19 mice.
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