| Strain Name |
C57BL/6-Il4tm2(IL4)Bcgen Il4ratm1(IL4RA)Bcgen Il13tm1(IL13)Bcgen Il13ra1tm1(IL13RA1)Bcgen /Bcgen |
Common Name | B-hIL4/hIL4RA/hIL13/hIL13RA1 mice |
| Background | C57BL/6 | Catalog number | 112812 |
| Aliases |
IL4: interleukin 4 IL4RA: interleukin 4 receptor, IL4R Il13: interleukin 13 IL13RA1: CD213A1, CT19, IL-13Ra, NR4 |
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Strain specific IL4 expression analysis in homozygous B-hIL4/hIL4RA/hIL13/hIL13RA1 mice by ELISA. Serum were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hIL4/hIL4RA/hIL13/hIL13RA1mice (H/H; H/H; H/H; H/H) stimulated with anti-mCD3Ɛ antibody in vivo, and analyzed by ELISA with species-specific IL4 ELISA kit. Mouse IL4 was detectable in wild-type C57BL/6 mice. Human IL4 was exclusively detectable in homozygous B-hIL4/hIL4RA/hIL13/hIL13RA1 mice, but not in wild-type mice.
Strain specific IL4RA expression analysis in homozygous B-hIL4/hIL4RA/hIL13/hIL13RA1 mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hIL4/hIL4RA/hIL13/hIL13RA1 mice (H/H; H/H; H/H; H/H), and analyzed by flow cytometry with species-specific anti-IL4RA antibody. Mouse IL4RA was detectable in wild-type mice, Human IL4RA was exclusively detectable in homozygous B-hIL4/hIL4RA/hIL13/hIL13RA1 mice, but not in wild-type mice.
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