B-hRSPO1 mice
| Strain Name |
C57BL/6N-Rspo1tm1(RSPO1)Bcgen/Bcgen
|
Common Name | B-hRSPO1 mice |
| Background | C57BL/6N | Catalog number | 110900 |
|
Related Genes |
R-spondin 1, RSPO; CRISTIN3 | ||
|
NCBI Gene ID |
192199 | ||
mRNA expression analysis
Strain specific analysis of RSPO1 gene expression in WT and B-hRSPO1 mice by RT-PCR.
Mouse Rspo1 mRNA was detectable in kidney of wild-type (+/+). Human RSPO1 mRNA was detectable only in H/H but not in +/+ mice.
Protein expression analysis
Strain specific analysis of RSPO1 expression in WT and B-hRSPO1 mice by western blot.
Liver tissue was collected from wild type C57BL/6 mice (+/+) and homozygous B-hRSPO1 mice (H/H), and analyzed by western blot with anti-RSPO1 antibody, which reacts with human and mouse RSPO1 proteins. RSPO1 was detectable in the liver of B-hRSPO1 mice (H/H) and wild type mice.
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