Strain Name
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C57BL/6-Sosttm1(SOST)Bcgen/Bcgen
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Common Name
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B-hSOST mice
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Background
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C57BL/6
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Catalog number
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110111
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Related Genes
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SOST (Sclerostin), CDD, DAND61, VBCH
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NCBI Gene ID
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74499
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mRNA expression analysis
Strain specific analysis of SOST gene expression in C57BL/6(+/+) and homozygous B-hSOST mice by RT-PCR.
Mouse Sost mRNA was detectable only in heart and testis of C57BL/6(+/+) mice. Human SOST mRNA was detectable only in homozygous B-hSOST mice, but not in C57BL/6(+/+) mice.
Protein expression analysis
Strain specific analysis of SOST gene expression in C57BL/6(+/+) and homozygous B-hSOST(H/H) mice by western blot.
Heart were collected from C57BL/6(+/+) and homozygous B-hSOST (H/H) mice. SOST was detectable in the heart of the C57BL/6(+/+) and B-hSOST (H/H) mice due to the cross-reactivity of antibodies.