Strain Name
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C57BL/6N-Slc3a2tm1(SLC3A2)Rag2tm1/Bcgen
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Common Name
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B-hCD98HC/Rag2 KO mice
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Background
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C57BL/6N
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Catalog number
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112326
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Related Genes
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SLC3A2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE,
CD98 heavy chain; RAG2, RAG-2, recombination activating 2
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Protein expression analysis in brain endothelial cells
Strain specific CD98 expression analysis in homozygous B-hCD98/Rag2 KO mice by flow cytometry. Brain were collected from wild type (WT) mice (+/+) and homozygous B-hCD98HC/Rag2 KO mice (H/H;-/-), and analyzed by flow cytometry with species-specific anti-CD98 antibody after trypsin digestion. Mouse CD98 was detectable in WT mice (+/+). Human CD98 was exclusively detectable in homozygous B-hCD98HC/Rag2 KO mice (H/H;-/-) but not in WT mice (+/+).
Protein expression analysis in T cells
Strain specific CD98 expression analysis in homozygous B-hCD98HC/Rag2 KO mice by flow cytometry. Splenocytes were collected from wild type (WT) mice (+/+) and homozygous B-hCD98HC/Rag2 KO mice (H/H;-/-), and analyzed by flow cytometry with species-specific anti-CD98 antibody. Mouse CD98 was detectable in WT mice (+/+) and human CD98 was not detectable in WT mice (+/+). There were no T cells in homozygous B-hCD98HC/Rag2 KO mice.
Protein expression analysis in B cells
Strain specific CD98 expression analysis in homozygous B-hCD98HC/Rag2 KO mice by flow cytometry. Splenocytes were collected from wild type (WT) mice (+/+) and homozygous B-hCD98HC/Rag2 KO mice (H/H;-/-), and analyzed by flow cytometry with species-specific anti-CD98 antibody. Mouse CD98 was detectable in WT mice (+/+) and human CD98 was not detectable in WT mice (+/+). There were no B cells in homozygous B-hCD98HC/Rag2 KO mice.
Protein expression analysis in NK cells
Strain specific CD98 expression analysis in homozygous B-hCD98HC/Rag2 KO mice by flow cytometry. Splenocytes were collected from wild type (WT) mice (+/+) and homozygous B-hCD98HC/Rag2 KO mice (H/H;-/-), and analyzed by flow cytometry with species-specific anti-CD98 antibody. Mouse CD98 was detectable in WT mice (+/+). Human CD98 was exclusively detectable in homozygous B-hCD98HC/Rag2 KO mice (H/H;-/-) but not in WT mice (+/+).